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References 1. The perineal cleansing should ideally be in the squatting positions so the anal canal is washed of retained faeces. Pruritus ani is a common condition with many causes, anal itch and anestesia anorectal pathology. Click here for the Professional Version. Avoiding irritating soaps and creams, and keeping the skin cool, dry, and clean is essential. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world.